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Page 1
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage.
González-Recio I, Simón J, Goikoetxea-Usandizaga N, Serrano-Maciá M, Mercado-Gómez M, Rodríguez-Agudo R, Lachiondo-Ortega S, Gil-Pitarch C, Fernández-Rodríguez C, Castellana D, Latasa MU, Abecia L, Anguita J, Delgado TC, Iruzubieta P, Crespo J, Hardy S, Petrov PD, Jover R, Avila MA, Martín C, Schaeper U, Tremblay ML, Dear JW, Masson S, McCain MV, Reeves HL, Andrade RJ, Lucena MI, Buccella D, Martínez-Cruz LA, Martínez-Chantar ML. González-Recio I, et al. Among authors: mccain mv. Nat Commun. 2022 Nov 25;13(1):6816. doi: 10.1038/s41467-022-34262-0. Nat Commun. 2022. PMID: 36433951 Free PMC article.
Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation.
Zadran B, Sudhindar PD, Wainwright D, Bury Y, Luli S, Howarth R, McCain MV, Watson R, Huet H, Palinkas F, Berlinguer-Palmini R, Casement J, Mann DA, Oakley F, Lunec J, Reeves H, Faulkner GJ, Shukla R. Zadran B, et al. Among authors: mccain mv. Br J Cancer. 2023 Mar;128(7):1236-1248. doi: 10.1038/s41416-023-02154-9. Epub 2023 Jan 27. Br J Cancer. 2023. PMID: 36707636 Free PMC article.
A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?
Eldafashi N, Darlay R, Shukla R, McCain MV, Watson R, Liu YL, McStraw N, Fathy M, Fawzy MA, Zaki MYW, Daly AK, Maurício JP, Burt AD, Haugk B, Cordell HJ, Bianco C, Dufour JF, Valenti L, Anstee QM, Reeves HL. Eldafashi N, et al. Among authors: mccain mv. Cancers (Basel). 2021 Mar 19;13(6):1412. doi: 10.3390/cancers13061412. Cancers (Basel). 2021. PMID: 33808740 Free PMC article.
Cell-free DNA TAPS provides multimodal information for early cancer detection.
Siejka-Zielińska P, Cheng J, Jackson F, Liu Y, Soonawalla Z, Reddy S, Silva M, Puta L, McCain MV, Culver EL, Bekkali N, Schuster-Böckler B, Palamara PF, Mann D, Reeves H, Barnes E, Sivakumar S, Song CX. Siejka-Zielińska P, et al. Among authors: mccain mv. Sci Adv. 2021 Sep 3;7(36):eabh0534. doi: 10.1126/sciadv.abh0534. Epub 2021 Sep 1. Sci Adv. 2021. PMID: 34516908 Free PMC article.
Key features of the environment promoting liver cancer in the absence of cirrhosis.
Zaki MYW, Mahdi AK, Patman GL, Whitehead A, Maurício JP, McCain MV, Televantou D, Abou-Beih S, Ramon-Gil E, Watson R, Cox C, Leslie J, Wilson C, Govaere O, Lunec J, Mann DA, Nakjang S, Oakley F, Shukla R, Anstee QM, Tiniakos D, Reeves HL. Zaki MYW, et al. Among authors: mccain mv. Sci Rep. 2021 Aug 18;11(1):16727. doi: 10.1038/s41598-021-96076-2. Sci Rep. 2021. PMID: 34408183 Free PMC article.
Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease.
Pelusi S, Baselli G, Pietrelli A, Dongiovanni P, Donati B, McCain MV, Meroni M, Fracanzani AL, Romagnoli R, Petta S, Grieco A, Miele L, Soardo G, Bugianesi E, Fargion S, Aghemo A, D'Ambrosio R, Xing C, Romeo S, De Francesco R, Reeves HL, Valenti LVC. Pelusi S, et al. Among authors: mccain mv. Sci Rep. 2019 Mar 6;9(1):3682. doi: 10.1038/s41598-019-39998-2. Sci Rep. 2019. PMID: 30842500 Free PMC article.
The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.
Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F. Bartneck M, et al. Among authors: mccain mv. Cell Mol Gastroenterol Hepatol. 2019;7(2):371-390. doi: 10.1016/j.jcmgh.2018.10.007. Epub 2018 Oct 18. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30704985 Free PMC article.
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.
Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: mccain mv. Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x. Nat Commun. 2017. PMID: 29233977 Free PMC article.